• Biologie
  • Santé

Biologie Cellulaire et Cancer

  • Unité mixte de recherche

Publié le 27/04/2020 - Mis à jour le 13/12/2024

Équipes

Direction

  • Franck Perez

Direction adjointe

  • Renata Basto

Publications sur HAL - Archive ouverte

Toutes les publications sur HAL
  • Article dans une revue

Optimization of the VSV-G backbone for amino terminal fusion with nanobodies allowing its specific retargeting to HER2 receptors

Isoline Duquénois, Stéphanie Thébault, Sarah Johari, Hélène Raux, Malika Ouldali, Sandrine Moutel, Cécile Lagaudrière-Gesbert, Franck Perez, Aurélie A Albertini, Yves Gaudin

Vesicular stomatitis virus (VSV) is a promising oncolytic virus.<p>Additionally, its glycoprotein G (VSV-G) is the most commonly used envelope glycoprotein to pseudotype lentiviral vectors for gene therapy. However, VSV receptors (low-density lipoprotein receptor [LDL-R] family members) are…

Molecular Therapy: Oncology, 2025, 33 (4), pp.201065. ⟨10.1016/j.omton.2025.201065⟩. ⟨hal-05378814⟩

  • Article dans une revue

Intermediate filaments promote glioblastoma cell invasion by controlling nuclear deformations and mechanosensitive expression of MMP14

Emma J van Bodegraven, Elvira Infante, Florent Peglion, David Pereira, Yekta Kesenci, Vanessa Roca, Isabelle Perfettini, Emmanuel Terriac, Juliana Geay, Laura Soto, Jacqueline Sluijs, Reinier Rietveld, Shailaja Seetharaman, Batiste Boëda, Jean-Christophe Olivo-Marin, Atef Asnacios, Aleix Boquet-Pujadas, Jean-Baptiste Manneville, Sandrine Etienne-Manneville

Glioblastoma (GBM), the most aggressive primary brain tumor, is marked by high invasiveness that enables resistance to current therapies. Single-cell RNA sequencing analysis reveals that elevated expression of glial intermediate filament (IF) genes correlates with pro-invasive markers in GBM…

Cell Reports, 2025, 44 (11), pp.116553. ⟨10.1016/j.celrep.2025.116553⟩. ⟨pasteur-05390219⟩

  • Pré-publication, Document de travail

Torque-based immune cell chemotaxis in complex environments

Theresa Jakuszeit, Mathieu Deygas, Mathilde Bernard, Aastha Mathur, Li Wang, Lisa Behrend, Pablo J Sáez, Pablo Vargas, Raphaël Voituriez, Matthieu Piel

Directed migration in chemical gradients is crucial to the immune response, yet how immune cells navigate complex tissues remains incompletely understood. Using in vitro migration assays and theoretical modeling, we uncover distinct chemotactic strategies in two key immune cell types: neutrophils…

2025. ⟨hal-05401063⟩

  • Pré-publication, Document de travail

CD133 shapes extracellular vesicle cargo and angiogenic function in basal-like triple-negative breast cancer

Mireia Gomez-Duro, Ptissam Bergam, Lorena Martin-Jaular, Sara Sanchez-Redondo, Marta Hergueta-Redondo, Florent Dingli, Damarys Loew, Hector Peinado, Thierry Dubois, Graca Raposo, Gisela D’angelo

Extracellular vesicles (EVs) are central mediators of tumor-stroma communication, yet the mechanisms governing their biogenesis and functional cargo remain poorly understood. Here, we identify CD133 (Prominin-1), selectively expressed in basal-like triple-negative breast cancer (BL-TNBC) cells, as…

2025. ⟨hal-05345954⟩

Toutes les publications sur HAL

Contacts

Adresse postale

Biologie Cellulaire et Cancer, Institut Curie, 26 rue d’Ulm, 75248 Paris Cedex 05 France
Adresse physique
Biologie Cellulaire et Cancer
Institut Curie
26 rue d’Ulm
75248 Paris Cedex 05 France
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